Maerua angolensis DC. (Capparaceae) Stem Bark Extract Protects against Pentylenetetrazole-Induced Oxidative Stress and Seizures in Rats

Figure 4

Effects of MAE (300 mg kg⁻¹) on the ((a) and (d)) duration, ((b) and (e)) latency, and ((c) and (f)) number of clonic convulsions for a 30-minute test period in the pentylenetetrazole-induced convulsions after pretreatment with L-arginine ((a), (b), and (c)) and sildenafil ((d), (e), and (f)). Data are expressed as group mean ± SEM. , , and indicate significant difference compared to control (one-way ANOVA followed by Sidak post hoc test). ^†, ^††, and ^††† indicate significant difference when treated and untreated rats were compared (two-way repeated-measures ANOVA followed by Bonferroni’s post hoc test).