Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2018 (2018), Article ID 9727240, 7 pages
https://doi.org/10.1155/2018/9727240
Research Article

Study of Pharmacodynamic and Pharmacokinetic Interaction of Bojungikki-Tang with Aspirin in Healthy Subjects and Ischemic Stroke Patients

1Department of Internal Medicine, College of Korean Medicine, Kyung Hee University, 23 Kyungheedae-ro, Dongdaemun, Seoul 02447, Republic of Korea
2Department of Pharmacology, School of Medicine, Kyung Hee University, 23 Kyungheedae-ro, Dongdaemun, Seoul 02447, Republic of Korea

Correspondence should be addressed to Byung-Cheol Lee; rk.ca.uhk@eelordyh

Received 26 October 2017; Accepted 24 December 2017; Published 23 January 2018

Academic Editor: Rentian Wu

Copyright © 2018 Jung-Hwa Yoo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. N. Asher, A. H. Corbett, and R. L. Hawke, “Common herbal dietary supplement-drug interactions,” American Family Physician, vol. 96, no. 2, pp. 101–107, 2017. View at Google Scholar
  2. M. de Lima Toccafondo Vieira and S.-M. Huang, “Botanical-drug interactions: a scientific perspective,” Planta Medica, vol. 78, no. 13, pp. 1400–1415, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Fugh-Berman, “Herb-drug interactions,” The Lancet, vol. 355, no. 9198, pp. 134–138, 2000. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Tachjian, V. Maria, and A. Jahangir, “Use of herbal products and potential interactions in patients with cardiovascular diseases,” Journal of the American College of Cardiology, vol. 55, no. 6, pp. 515–525, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. X. Q. Wang, T. Takahashi, S. Zhu et al., “Effect of Hochu-ekki-to (TJ-41), a japanese herbal medicine, on daily activity in a murine model of chronic fatigue syndrome,” Evidence-Based Complementary and Alternative Medicine, vol. 1, no. 2, pp. 203–206, 2004. View at Publisher · View at Google Scholar
  6. J.-N. K. In-Seon Choi and K. Young-Kyun, “Neurological effects of bojungikki-tang and bojungikki-tang-gamibang on focal cerebral ischemia of the MCAO rats,” The Journal of Korean Oriental Medicine, vol. 30, no. 6, pp. 53–86, 2009. View at Google Scholar
  7. H. Kuratsune, “Effect of Kampo Medicine, "Hochu-ekki-to", on chronic fatigue syndrome,” Clinic and Research, vol. 74, pp. 1837–1845, 1997. View at Google Scholar
  8. V. Scheid, D. Bensky, A. Ellis, and R. Barolet, Chinese herbal medicine: formulas strategies, Eastland Press, 2009.
  9. W. Abebe, “Herbal medication: potential for adverse interactions with analgesic drugs,” Journal of Clinical Pharmacy and Therapeutics, vol. 27, no. 6, pp. 391–401, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Gao, X. Xu, and S. Ni, “Research on antithrombotic effect of total saponins of astragalus,” Chinese Traditional Patent Medicine, vol. 24, no. 2, pp. 116–118, 2002. View at Google Scholar
  11. Y. Xu, P. Gao, and Q. Liang, “Experimental study on effect of astragalus polysaccharide to the cerebral thrombosis,” Chinese Journal of Hematology, vol. 9, no. 3, pp. 133–136, 1999. View at Google Scholar
  12. Q. Wang, J. Li, and Y. Liu, “Effect of astragalus injection on the formation of venous thrombosis in rats,” Chinese Traditional Patent Medicine, vol. 25, no. 6, 498 pages, 2003. View at Google Scholar
  13. Y. Wu, J. Ouyang, and S. Tu, “Effects of Astragalus Polysaccharides on atherosclerosis endothelial cell injury,” Journal of Hubei College of Traditional Chinese Medicine, vol. 4, no. 1, 21 pages, 2002. View at Google Scholar
  14. T.-H. Kim, H.-M. Kim, S. W. Park, and Y.-S. Jung, “Inhibitory effects of yuzu and its components on human platelet aggregation,” Biomolecules & Therapeutics, vol. 23, no. 2, 149 pages.
  15. D. M. Becker, J. Segal, D. Vaidya et al., “Sex differences in platelet reactivity and response to low-dose aspirin therapy,” The Journal of the American Medical Association, vol. 295, no. 12, pp. 1420–1427, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. J. Heo, Translated Dongeuibogam, Translated Dongeuibogam, Seoul, 1999.
  17. J. Gruenwald, T. Brendler, and C. Jaenicke, PDR for Herbal Medicines, Medical Economics Company, Inc, Montvale, NJ, USA, 1998.
  18. S.-C. Kuo, C.-M. Teng, J.-C. Lee, F.-N. Ko, S.-C. Chen, and T.-S. Wu, “Antiplatelet components in panax ginseng,” Planta Medica, vol. 56, no. 2, pp. 164–167, 1990. View at Publisher · View at Google Scholar · View at Scopus
  19. H.-J. Park, J.-H. Lee, Y.-B. Song, and K.-H. Park, “Effects of dietary supplementation of lipophilic fraction from Panax ginseng on cGMP and cAMP in rat platelets and on blood coagulation,” Biological & Pharmaceutical Bulletin, vol. 19, no. 11, pp. 1434–1439, 1996. View at Publisher · View at Google Scholar · View at Scopus
  20. B. J. Gurley, S. F. Gardner, M. A. Hubbard et al., “Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba,” Drugs & Aging, vol. 22, no. 6, pp. 525–539, 2005. View at Publisher · View at Google Scholar · View at Scopus
  21. T. Fujita, A. Kawase, T. Niwa et al., “Comparative evaluation of 12 immature citrus fruit extracts for the inhibition of cytochrome P450 isoform activities,” Biological & Pharmaceutical Bulletin, vol. 31, no. 5, pp. 925–930, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. J. Bigler, J. Whitton, J. W. Lampe, L. Fosdick, R. M. Bostick, and J. D. Potter, “CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk,” Cancer Research, vol. 61, no. 9, pp. 3566–3569, 2001. View at Google Scholar · View at Scopus