| Author (year) | Participants group:n(f)/ mean age | Acupuncture groups | Control groups | Outcomes | Results | Acupuncture | acupoints number, duration | Control | acupoints number, duration |
| (1) Thomas et al. (1995) [17] | Primary dysmenorrhea Acu: 17(17)/30.4 Con: 12(12)/27.8 | (a) MA (b) EA (2Hz) (c) EA (100Hz) (d) Periosteal stimulation (e) acu-TENS (2Hz) (f) acu-TENS (100Hz) | (a), (b), (c), (d): BL32, CV4, SP6, 9 (e), (f): Spinous processes Thoracic 10-Lumbar 1 2, 20min | (g) Sham TENS (ns) | Spinous processes Thoracic 10-Lumbar 1 2, 20min | (1) Blood loss (2) Vomiting (3) Work hours lost (4) Tablet intake (5) Subjective assessment (6) Total pain | Within group (4), (5), (6) (a), (c), (d) improved (5), (6) (b) improved (4), (5), (6) (e) improved | (2) Kotani et al. (2001) [19] | (1) Upper abdominal surgery (A) 50(21)/52 (C) 48(18)/55 (2) Lower abdominal surgery (B) 39(12)/55 (D) 38(13)/55 | (A) Patient 1 +MA (B) Patient 2 +MA | (A) BL18, 19, 20, 21, 22, 23, 24 (B) BL20, 21, 22, 23, 24, 25, 26 1, 4 days | (C) Patient 1+sham MA (ni) (D) Patient 2+sham MA (ni) | (C) BL18, 19, 20, 21, 22, 23, 24 (D) BL20, 21, 22, 23, 24, 25, 26 1, 4 days | (1) Incisional, visceral pain (2) Drowsiness (3) Pruritus (4) Nausea/Vomiting (5) Adequacy of pain treatment (6) Morphine intake (7) Adrenal hormone | Within group (1) (A), (C) improved (6) (A), (B), (C), (D) decreased Between groups (1), (4), (6), (7) (epinephrine, cortisol) (A)<(C), (B)<(D) | (3) Xing et al. (2004) [16] | IBS +rectal distention 7(6)/44 | (a) acu-TENS (5Hz, 250ms) | (a) ST36, PC6 1, - | (b) TENS (5Hz, 250ms) | (b) non-acupoint 1, - | (1) Rectal tone (2) Rectal compliance (3) Rectal perception of gas, pain, desire to defecate | Within group (1) (A), (B) decreased (3) (A) decreased Between groups (3) (A)<(B) | (4) Chu et al. (2012) [15] | IBS +rectal distention (A) 15(7)/42.3 (B) 15(8)/44.2 | (A) EA (10Hz, 0.5ms, 60v) | (A) ST36, 37, SP6 2, 30min | (B) Sham EA (ns) | (B) ST36, 37, SP6 2, 30min | (1) fMRI-rectal distention (2) fMRI-A or B +rectal distention (3) fMRI-rectal distention after (2) (4) fMRI-A or B (5) Rectal sensation | Within group (1) (A), (B): ACC, pgCC, PFC, TH, INS, cerebellum, Temp (A): (1)<(2) pgCC, ACC, PFC, SC, INS, Temp (1)<(3) PFC, SC, Temp (3)<(2) ACC, PFC, TH, INS, Temp (B): (2)>(1) ACC, PFC, SC (3)>(1) PFC, Temp, cerebellum (2)>(3) Temp (3)>(2) PFC Between groups (A)>(B): (2)>(1) in TH, INS Correlation between (5) and brain activation in hypothalamus, TH, INS | (5) Leung et al. (2013) [20] | Healthy +rectal distention (A) 20(12)/53.4 (B) 20(12)/53.9 | (A) acu-TENS (2Hz, 0.2ms) | (A) LI4, PC6, ST36 1, 45min | (B) Sham TENS (ns) | (B) LI4, PC6, ST36 1, 45min | (1) Tolerance to rectal sensation (2) Rectal distention pressure (3) Beta-endorphin | Between groups (1), (2), (3) (B)<(A) | (6) Juel et al. (2016) [21] | Healthy +rectal distention 15(8)/27.6 | (a) MA | (a) CV4, 6, 7, 9, 10, 12, ST25, 26, 37, LI4 +non-acupoints 1, 30min | (b) Sham MA (ni) | (b) ST37, LI4 1, 30min | (1) Rectal distention volume (2) Rectal pain (3) EEG | Within groups (1) (A), (B) increased | (7) Juel et al. (2017) [18] | Chronic pancreatitis 15(7)/61.8 | (a) MA | (a) CV4, 6, 9, 10, 12, ST25, ST36, SP6, 8, 9, 15+non-acupoints 1, - | (b) Sham MA (ni) | (b) CV4, 6, 9, 10, 12, ST25, ST36, SP6, 8, 9, 15+non-acupoints 1, - | (1) Reduced pain score (2) EEG | Between groups (1) (B)<(A) |
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