Research Article

Intestinal Absorption Profile of Three Polygala Oligosaccharide Esters in Polygalae Radix and the Effects of Other Components in Polygalae Radix on Their Absorption

Table 2

Absorption parameters of SA5, SA6, and DISS in the intestines of rats (; n = 5).

CompoundConcentration (mg/ml) (μg·cm−2·min−1) (×10−5cm/min) (%)

SA50.0250.0091 ± 0.00110.61 ± 0.0702.59 ± 0.23
0.0500.031 ± 0.00121.05 ± 0.0394.33 ± 0.13
0.0750.033 ± 0.00140.73 ± 0.0323.16 ± 0.07
SA60.0430.020 ± 0.00170.77 ± 0.0653.29 ± 0.25
0.0860.041 ± 0.00410.80 ± 0.0793.64 ± 0.27
0.1300.048 ± 0.0040,0.62 ± 0.522.79 ± 0.11
DISS0.0990.015 ± 0.00050.26 ± 0.0681.13 ± 0.05
0.1980.032 ± 0.00150.27 ± 0.0131.15 ± 0.04
0.2960.049 ± 0.022 0.28 ± 0.0791.18 ± 0.04

< 0.01 and < 0.05, compared with low dose; < 0.01 and < 0.05, compared with medium dose.