Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Tab 4

Research Article

Phytochemical Analysis and Toxicity Study of Aristolochia paucinervis Rhizomes Decoction Used in Moroccan Alternative Medicine: Histopathological and Biochemical Profiles

Table 4

Results of Tukey test for comparisons between groups regarding lesions in the kidney (subacute toxicity).

Histopathology of kidneycontrol group vs. group 1control group vs. group 2control group vs. group 3group 1 vs. group 2group 1 vs. group 3group 2 vs. group 3

Tubular necrosis10.190.0080.110.0080.58
Hyaline necrosis10.730.0490.730.0490.19
Coagulation necrosis110.3810.380.38
Inflammatory infiltrate10.150.030.150.030.33
Extended coagulation111111
Altered tissue architecture111111
Cell vacuolization110.3510.350.53
Tubular degeneration10.740.470.740.470.93
Cell congestion10.220.060.220.060.52
Tubular atrophy111111
Interstitial fibrosis111111
Vascular dilation110.00910.0090.009

Control: normal diet; group 1: normal diet + 0.5 g/kg/day extract; group 2: normal diet + 1 g/kg/day extract; group 3: normal diet + 1.5 g/kg/day extract. : significant at 5% level.

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