Combined Extracts of Herba Epimedii and Fructus Ligustri Lucidi Rebalance Bone Remodeling in Ovariectomized Rats

Figure 6

Effects of HE & FLL on OPG, IGF-1, TGF-β1, and Bmp-2 in OVX rats. (a) The mRNA expressions of OPG, IGF-1, TGF-β, and Bmp-2 were measured by qRT-PCR analysis with β-actin as an internal control. (b) The protein expressions of OPG, IGF-1, TGF-β1, and Bmp-2 were measured by immunofluorescence staining. (c) Immunofluorescence images of OPG, IGF-1, TGF-β1, and Bmp-2. Data are represented as mean ± SEM, n = 6. Note: < 0.01 versus Sham; < 0.05 and < 0.01 versus OVX.

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