Research Article

The Variant at TGFBRAP1 but Not TGFBR2 Is Associated with Antituberculosis Drug-Induced Liver Injury

Table 5

Quantitative indicator comparisons among genotypes of rs17687727 in TGFBRAP1.

Laboratory indicatorsGenotype
GGGAAA

TBIL (μmol/L)a12.15 (7.15–18.44)13.40 (9.70–19.55)10.35 (6.85–17.67)0.48
DBIL (μmol/L)a5.65 (3.25–10.40)5.60 (3.95–8.79)3.90 (3.80–4.98)0.45
IBIL (μmol/L)a4.90 (3.57–8.12)6.60 (4.74–10.2)6.45 (3.00–12.75)0.08
ALT (IU/L)a108.00 (50.50–191.75)164.00 (105.00–316.00)91.00 (38.00–250.50)0.03
AST (IU/L)a83.00 (38.50–160.25)115.00 (72.50–217.00)200.50 (100.50–276.50)0.03
ALP (IU/L)a108.5 (75.25–189.25)98.00 (71.50–126.50)97.50 (77.75–129.25)0.32

aData are shown as median (interquartile range).