Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Tab 2

Research Article

The Tissue Distribution of Four Major Coumarins after Oral Administration of Angelicae Pubescentis Radix Extract to Rats Using Ultra-High-Performance Liquid Chromatography

Table 2

The recoveries of columbianetin, columbianetin acetate, osthole, and columbianadin.

Tissuescolumbianetincolumbianetin acetate
LowMiddleHighLowMiddleHigh
RecoveryRSDRecoveryRSDRecoveryRSDRecoveryRSDRecoveryRSDRecoveryRSD
(%)(%)(%)(%)(%)(%)(%)(%)(%)(%)(%)(%)

Heart81.83.9694.61.7293.80.6992.83.8082.84.7483.82.55
Liver87.82.6788.70.7294.21.5785.77.0382.110.587.12.97
Spleen89.54.0999.11.5597.41.9380.89.6380.73.9293.21.19
Lung97.72.5899.48.7197.81.4684.310.385.89.4686.15.15
Kidney97.44.6495.85.8095.50.6184.64.7181.14.7591.73.02
Uterus93.08.5495.78.8397.33.6597.61.0286.24.1388.47.43
Ovary99.35.8292.63.2897.97.4083.110.485.75.7589.55.21
Muscle92.16.4293.90.3593.80.7491.36.0498.33.2290.15.71

Tissuesostholecolumbianadin
LowMiddleHighLowMiddleHigh
RecoveryRSDRecoveryRSDRecoveryRSDRecoveryRSDRecoveryRSDRecoveryRSD
(%)(%)(%)(%)(%)(%)(%)(%)(%)(%)(%)(%)

Heart91.27.7098.62.7594.33.5582.11.8380.24.7388.41.13
Liver93.14.4294.65.8793.15.9381.34.8481.91.9284.35.68
Spleen95.16.4095.77.6190.93.3381.03.1183.16.1991.92.00
Lung94.39.3799.81.3892.35.7496.57.3289.01.3290.03.05
Kidney94.910.8897.14.0895.57.4292.21.7395.31.2691.40.81
Uterus88.210.5196.52.3399.95.1194.39.5799.22.7296.57.75
Ovary93.83.7694.76.1193.95.6396.83.4198.44.0998.47.47
Muscle97.35.2989.20.9091.92.6892.65.7798.24.7697.63.20