The Tissue Distribution of Four Major Coumarins after Oral Administration of Angelicae Pubescentis Radix Extract to Rats Using Ultra-High-Performance Liquid Chromatography

Table 2

The recoveries of columbianetin, columbianetin acetate, osthole, and columbianadin.

Tissues	columbianetin						columbianetin acetate
	Low		Middle		High		Low		Middle		High
	Recovery	RSD	Recovery	RSD	Recovery	RSD	Recovery	RSD	Recovery	RSD	Recovery	RSD
	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)
Heart	81.8	3.96	94.6	1.72	93.8	0.69	92.8	3.80	82.8	4.74	83.8	2.55
Liver	87.8	2.67	88.7	0.72	94.2	1.57	85.7	7.03	82.1	10.5	87.1	2.97
Spleen	89.5	4.09	99.1	1.55	97.4	1.93	80.8	9.63	80.7	3.92	93.2	1.19
Lung	97.7	2.58	99.4	8.71	97.8	1.46	84.3	10.3	85.8	9.46	86.1	5.15
Kidney	97.4	4.64	95.8	5.80	95.5	0.61	84.6	4.71	81.1	4.75	91.7	3.02
Uterus	93.0	8.54	95.7	8.83	97.3	3.65	97.6	1.02	86.2	4.13	88.4	7.43
Ovary	99.3	5.82	92.6	3.28	97.9	7.40	83.1	10.4	85.7	5.75	89.5	5.21
Muscle	92.1	6.42	93.9	0.35	93.8	0.74	91.3	6.04	98.3	3.22	90.1	5.71
Tissues	osthole						columbianadin
	Low		Middle		High		Low		Middle		High
	Recovery	RSD	Recovery	RSD	Recovery	RSD	Recovery	RSD	Recovery	RSD	Recovery	RSD
	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)
Heart	91.2	7.70	98.6	2.75	94.3	3.55	82.1	1.83	80.2	4.73	88.4	1.13
Liver	93.1	4.42	94.6	5.87	93.1	5.93	81.3	4.84	81.9	1.92	84.3	5.68
Spleen	95.1	6.40	95.7	7.61	90.9	3.33	81.0	3.11	83.1	6.19	91.9	2.00
Lung	94.3	9.37	99.8	1.38	92.3	5.74	96.5	7.32	89.0	1.32	90.0	3.05
Kidney	94.9	10.88	97.1	4.08	95.5	7.42	92.2	1.73	95.3	1.26	91.4	0.81
Uterus	88.2	10.51	96.5	2.33	99.9	5.11	94.3	9.57	99.2	2.72	96.5	7.75
Ovary	93.8	3.76	94.7	6.11	93.9	5.63	96.8	3.41	98.4	4.09	98.4	7.47
Muscle	97.3	5.29	89.2	0.90	91.9	2.68	92.6	5.77	98.2	4.76	97.6	3.20