Active Ingredients and Action Mechanisms of Yi Guan Jian Decoction in Chronic Hepatitis B Patients with Liver Fibrosis

Figure 3

(a) PPI network of the CHB with LKYDS genes. The red nodes represent the genes associated with liver fibrosis, which were selected as potential targets. The sizes of the nodes are proportional to the values of their corresponding DC scores. (b) Results of the pathway enrichment analysis of the CHB with LKYDS genes, the potential targets, and others (genes not selected as potential targets). The sizes of the bubbles represent the gene ratios, which were calculated using the ratio of the pathway-related genes to the total number of gene sets. Only the top 20 enrichment items of the potential targets are shown in the figure. (c) Comparison of the mean values of the DC scores and the BC scores between the selected and the other genes in the network. in the t-test for the two independent samples. The standard deviation is shown as the error bar in the chart.

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