Active Ingredients and Action Mechanisms of Yi Guan Jian Decoction in Chronic Hepatitis B Patients with Liver Fibrosis

Table 2

Main targets of the YGJD in the treatment of CHB-related liver fibrosis.

Symbol	Entrez ID	Protein name	BC (10^−3)
RELA	5970	Transcription factor p65, NF-κB subunit	5.28
EGFR	1956	Epidermal growth factor receptor	2.66
RAC3	5881	Ras-related C3 botulinum toxin substrate 3	1.44
FOS	2353	Proto-oncogene c-Fos, AP-1 transcription factor subunit	1.25
IFNA1	3439	Interferon-alpha 1/13	1.05
JUN	3725	Transcription factor AP-1	0.89
MAPK12	6300	Mitogen-activated protein kinase 12	0.61
FN1	2335	Fibronectin	0.59
INPP5B	3633	Type II inositol 1,4,5-trisphosphate 5-phosphatase	0.56
TGFB3	7043	Transforming growth factor-beta 3	0.47
RXRG	6258	Retinoic acid receptor RXR-gamma	0.45
CYP2C9	1559	Cytochrome P450 2C9	0.43
OCRL	4952	Inositol polyphosphate 5-phosphatase OCRL-1	0.36
IL1B	3553	Interleukin-1-beta	0.35
HGS	9146	Hepatocyte growth factor-regulated tyrosine kinase substrate	0.32