Yangyin Yiqi Mixture Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Rats through Inhibiting TGF-1/Smad Pathway and Epithelial to Mesenchymal Transition

Table 2

Histopathologic data of each group on 14d and 28d were presented as mean± SD (n=8). Compared with control group (p <0.05, p <0.01), compared with BLM group (p <0.05, p <0.01), compared with BLM + Pred group (p <0.05, p <0.01), and compared with BLM + YYYQ-L group (p <0.05, p <0.01).

Group	HE		Masson
	14d	28d	14d	28d
Control	0.10±0.30	0.00±0.00	0.05±0.22	0.03±0.16
BLM	2.11±0.93	1.75±0.97	1.87±0.81	2.43±0.71
BLM+ Pred	1.76±0.80	1.34±0.87	1.73±0.85	1.80±0.73
BLM+YYYQ-L	1.77±0.95	1.31±0.82	1.62±0.86	1.63±0.76
BLM+YYYQ-M	1.56±0.91	1.38±0.82	1.51±0.89	1.65±0.70
BLM+YYYQ-H	1.45±0.79	1.11±0.84	1.08±0.90	1.39±0.64