Research Article

Momordica charantia (Indian and Chinese Bitter Melon) Extracts Inducing Apoptosis in Human Lung Cancer Cell Line A549 via ROS-Mediated Mitochodria Injury

Table 1

Cytotoxic effect [IC50 (μg/mL)] of Momordica charantia extracts and standard drugs against A549 cell and MRC5 after 24 hrs incubation.

Cancer Cell LineNormal Cell Line
M. charantiaSolventsA549MRC5

Plant extractsChinese (C)Hot Aqueous (HA)32.5 ± 0.18>500
Cold Aqueous (CA)28.1 ± 0.19>500
Indian (I)Hot Aqueous (HA)36.9 ± 0.08>500
Cold Aqueous (CA)26.7 ± 0.05>500
Standard drugCisplatin17.3 ± 0.01