Phyllanthus muellerianus (Euphorbiaceae) Restores Ovarian Functions in Letrozole-Induced Polycystic Ovarian Syndrome in Rats

Figure 5

Effects of clomiphene citrate, metformin, aqueous and methanolic extracts of P. mullerianus on ovarian histology after 7 and 14 days of treatment. DW: distilled water; CC: clomiphene citrate; Met: metformin; AE: aqueous extract; ME: methanolic extract; CL: corpus luteum; CF: cystic follicle; AF: atretic follicle; PA: preantral follicle; A: antral follicle. Magnification x40. Calibration bar =100 μm.

(a) Control

(b) PCOS+DW (10 ml/kg)

(c) PCOS+CC (2 mg/kg)

(d) PCOS+Met (500 mg/kg)

(e) PCOS+EA (30 mg/kg)

(f) PCOS+EA (60 mg/kg)

(g) PCOS+EA (120 mg/kg)

(h) PCOS+EM (30 mg/kg)

(i) PCOS+EM (60 mg/kg)

(j) PCOS+ EM (120 mg/kg)

(k) Control

(l) PCOS+DW (10 ml/kg)

(m) PCOS+CC (2 mg/kg)

(n) PCOS+Met (500 mg/kg)

(o) PCOS+EA (30 mg/kg)

(p) PCOS+EA (60 mg/kg)

(q) PCOS+EA (120 mg/kg)

(r) PCOS+EM (30 mg/kg)

(s) PCOS+EM (60 mg/kg)

(t) PCOS+EM (120 mg/kg)