Research Article

Phyllanthus muellerianus (Euphorbiaceae) Restores Ovarian Functions in Letrozole-Induced Polycystic Ovarian Syndrome in Rats

Table 2

Percentage of PCOS rats with regular estrus cycle after treatments with clomiphene citrate, metformin, and aqueous and methanolic extracts of P. mullerianus for 14 days.

ā€‰ControlPCOS+DWPCOS+CCPCOS+METPCOS+AEPCOS+AEPCOS+AEPCOS+MEPCOS+MEPCOS+ME
(10 ml/kg)(2 mg/kg)(500 mg/kg)(30 mg/kg)(60 mg/kg)(120 mg/kg)(30 mg/kg)(60 mg/kg)(120 mg/kg)

D0-D4100000022.22022.2200
D5-D9100033.3322.2222.22044.4411.1144.4433.33
D10-D14100044.4433.3322.2233.3366.6766.6755.5644.44

Number of rats per group = 6. D: day; DW: distilled water; CC: clomiphene citrate; MET: metformin; AE: aqueous extract; ME: methanolic extract; PCOS: polycystic ovarian syndrome.