A Systems Pharmacology-Based Study of the Molecular Mechanisms of San Cao Decoction for Treating Hypertension

Figure 3

Identification of candidate targets for SCD against hypertension. (a) SCD shared 75 putative targets with known antihypertension drugs. The compound-putative target network was constructed by linking the overlapped targets (between SCD putative and known hypertension-related) and the homologous candidate compounds of SCD. The nodes representing candidate compounds are shown as polychrome rhombus and the targets are presented as grey circles. (b) Identification of candidate SCD targets for hypertension treatment through PPI network. 116 candidate targets are finally predicted.

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