Research Article
Baihu Jia Guizhi Decoction Improves Rheumatoid Arthritis Inflammation by Regulating Succinate/SUCNR1 Metabolic Signaling Pathway
Figure 6
Effects of BHGZ on succinate and the expression of SUCNR1. On the 42nd day of the experiment, the right ankle joint of the rats was cut and fixed with paraformaldehyde for immunohistochemical detection. (a) The content of succinate in synovial tissue (n = 5). (b) Correlation analysis of succinate and pathology. (c) Representative images of SUCNR1 immunohistochemistry in each group were exhibited (n = 3). (d) Correlation analysis of the expression of SUCNR1 and pathology. Data are mean ± S.D. illustrated the extraordinary difference compared with the AA group; and represent statistically significant differences compared with the AA + DHE group. BHGZ, Baihu Jia Guizhi decoction; AA, adjuvant arthritis; AA + DHE, AA with damp and heat environment.
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