Research Article

Preventive Effect of the Herbal Preparation, HemoHIM, on Cisplatin-Induced Immune Suppression

Table 1

Effect of HemoHIM on spleen and thymus weight change in cisplatin-treated mice.

GroupRelative organ weight (%)
SpleenThymus

Control0.218 ± 0.0130.171 ± 0.013
Cisplatin0.193 ± 0.0180.049 ± 0.024 ###
Cisplatin + HemoHIM 100 mg/kg0.205 ± 0.0150.046 ± 0.037
Cisplatin + HemoHIM 250 mg/kg0.212 ± 0.0220.053 ± 0.032
Cisplatin + HemoHIM 500 mg/kg0.197 ± 0.0210.047 ± 0.033

The body weight was measured on days 0, 4, 7, 11, and 13 and organ weight was measured on day 14.
Data are expressed as mean ± SD (n=7). Relative organ weight (%) = (organ weight)/(final body weight) x 100.
Comparison was made between control and cisplatin groups (###p<0.001).