Research Article

Preventive Effect of the Herbal Preparation, HemoHIM, on Cisplatin-Induced Immune Suppression

Table 2

Effect of HemoHIM on flow cytometric analysis CD4+ and CD8+T lymphocytes in cisplatin-treated mice.

GroupSplenocyteWhole blood
CD4+(%)CD8+(%)CD4+(%)CD8+(%)

Control54.77 ± 1.8636.46 ± 2.6615.04 ± 2.697.84 ± 2.32
Cisplatin51.91 ± 1.2839.20 ± 2.4614.87 ± 2.768.87 ± 1.07
Cisplatin + HemoHIM 100 mg/kg53.47 ± 2.3940.36 ± 2.5715.27 ± 2.778.70 ± 1.54
Cisplatin + HemoHIM 250 mg/kg56.07 ± 2.3739.13 ± 2.4915.63± 1.929.09 ± 1.57
Cisplatin + HemoHIM 500 mg/kg56.73 ± 3.2038.41 ± 2.3918.94 ± 3.5211.57 ± 2.62

Significant difference from cisplatin group (p<0.05, p<0.01).