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Evidence-Based Complementary and Alternative Medicine
Volume 2019, Article ID 3684601, 5 pages
https://doi.org/10.1155/2019/3684601
Research Article

Aiweixin, a Traditional Uyghur Medicinal Formula, Extends the Lifespan of Caenorhabditis elegans

1College of Xinjiang Uyghur Medicine, Hetian, Xinjiang 848000, China
2Pudong New Area Mental Health Center, Tongji University School of Medicine, Shanghai 200092, China
3Shanghai Research Center for Model Organisms, Shanghai 201203, China
4Tongji University School of Life Sciences and Technology, 200092, China

Correspondence should be addressed to Binggen Zhu; nc.ude.ijgnot@uhz.neggnib and Kaisaier Abudukerim; moc.361@ba_resiak

Received 15 March 2018; Revised 5 September 2018; Accepted 14 November 2018; Published 13 January 2019

Academic Editor: Omer Kucuk

Copyright © 2019 Binggen Zhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. P. O'Reilly, C. J. Luke, D. H. Perlmutter, G. A. Silverman, and S. C. Pak, “C. elegans in high-throughput drug discovery,” Advanced Drug Delivery Reviews, vol. 69-70, pp. 247–253, 2014. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Antebi, “Genetics of aging in Caenorhabditis elegans,” PLoS Genetics, vol. 3, no. 9, pp. 1565–1571, 2007. View at Google Scholar · View at Scopus
  3. H. A. Tissenbaum, “Genetics, life span, health span, and the aging process in caenorhabditis elegans,” Journals of Gerontology. Series A, Biological Sciences & Medical Sciences, vol. 67, no. 5, pp. 503–510, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Olsen, M. C. Vantipalli, and G. J. Lithgow, “Using Caenorhabditis elegans as a model for aging and age-related diseases,” Annals of the New York Academy of Sciences, vol. 1067, no. 1, pp. 120–128, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. Q. Wang, F. Yang, W. Guo et al., “Caenorhabditis elegans in Chinese medicinal studies: making the case for aging and neurodegeneration,” Rejuvenation Research, vol. 17, no. 2, pp. 205–208, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. F. Wan, D. Zhi, D. Liu et al., “Lifespan extension in Caenorhabiditis elegans by several traditional Chinese medicine formulas,” Biogerontology, vol. 15, no. 4, pp. 377–387, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. J. J. Collins, K. Evason, and K. Kornfeld, “Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans,” Experimental Gerontology, vol. 41, no. 10, pp. 1032–1039, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. K. Koch, S. Havermann, C. Büchter, and W. Wätjen, “Caenorhabditis elegans as model system in pharmacology and toxicology: Effects of flavonoids on redox-sensitive signalling pathways and ageing,” The Scientific World Journal, vol. 2014, Article ID 920398, 15 pages, 2014. View at Google Scholar · View at Scopus
  9. China Pharmacopoeia Commission, Drug Standard of Ministry of Public Health of the Peoples Republic of China (Uyghur Medicine), vol. 72, Xinjiang publishing house of science, technology and health, Urumqi, China, 1999.
  10. T. Jurat, A. Tuehong, and Q. Wu, “The clinical efficacy research of Aiweixin oral liquor in the treatment of coronary heart disease and myocardial ischemia,” Journal of Medicine & Pharmacy of Chinese Minorities, vol. 15, no. 4, pp. 10–13, 2009. View at Google Scholar
  11. A. Dilinul and H. Asya, “Uyghur medical guidelines for diagnosis and treatment of malihuliya (depression),” Journal of Medicine & Pharmacy of Chinese Minorities, vol. 17, no. 9, pp. 50-51, 2011. View at Google Scholar
  12. H. Asya, A. Dilinul, and H. Maimaiti, “Uyghur medical guidelines for diagnosis and treatment of cerebral infarction,” Journal of Medicine & Pharmacy of Chinese Minorities, vol. 16, no. 12, pp. 74-75, 2010. View at Google Scholar
  13. B. Zhu, P. Yang, N. Mammat et al., “Aiweixin, a traditional Uyghur medicinal formula, protects against chromium toxicity in Caenorhabditis elegans,” BMC Complementary and Alternative Medicine, vol. 15, p. 285, 2015. View at Publisher · View at Google Scholar · View at Scopus
  14. R. Wang, L. Wang, and Y. Liu, “Research on the protective effects of Aiweixin ischemia-reperfusion injury in liquid in myocardial rats,” Journal of Xinjiang Medical University, vol. 32, pp. 146–149, 2009. View at Google Scholar
  15. Y. M. Yuan, L. Wang, and R. Wang, “Influence of Aiweixin oral liquor on MPO and MDA in MIRI rat,” Journal of Xinjiang Medical University, vol. 33, pp. 33–35, 2010. View at Google Scholar
  16. F. Meng, J. Li, W. Wang, and Y. Fu, “Gengnianchun, a Traditional Chinese Medicine, Enhances Oxidative Stress Resistance and Lifespan in Caenorhabditis elegans by Modulating daf-16/FOXO,” Evidence-Based Complementary and Alternative Medicine, vol. 2017, Article ID 8432306, 10 pages, 2017. View at Publisher · View at Google Scholar
  17. Y. Zhao, A. F. Gilliat, M. Ziehm et al., “Two forms of death in ageing Caenorhabditis elegans,” Nature Communications, vol. 8, Article ID 15458, 2017. View at Publisher · View at Google Scholar
  18. Y. Kim, J. Lee, G. Gwon, S. Kim, J. G. Park, and J. Lee, “Essential Oils and Eugenols Inhibit Biofilm Formation and the Virulence of Escherichia coli O157:H7,” Scientific Reports, vol. 6, no. 1, Article ID 36377, 2016. View at Publisher · View at Google Scholar
  19. N. Saul, K. Pietsch, S. R. Stürzenbaum, R. Menzel, and C. E. Steinberg, “Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity,” Journal of Natural Products, vol. 74, no. 8, pp. 1713–1720, 2011. View at Google Scholar
  20. F. H. Abdel-Rahman, N. M. Alaniz, and M. A. Saleh, “Nematicidal activity of terpenoids,” Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes, vol. 48, no. 1, pp. 16–22, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. M. Asha, D. Prashanth, B. Murali, R. Padmaja, and A. Amit, “Anthelmintic activity of essential oil of Ocimum sanctum and eugenol,” Fitoterapia, vol. 72, no. 6, pp. 669-670, 2001. View at Publisher · View at Google Scholar
  22. S. Alper, M. K. McElwee, J. Apfeld, B. Lackford, J. H. Freedman, and D. A. Schwartz, “The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity,” The Journal of Biological Chemistry, vol. 285, no. 3, pp. 1822–1828, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. E. Yunger, M. Safra, M. Levi-Ferber, A. Haviv-Chesner, S. Henis-Korenblit, and M. Tan, “Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7,” PLoS Genetics, vol. 13, no. 2, Article ID e1006577, 2017. View at Publisher · View at Google Scholar
  24. O. Altintas, S. Park, and S.-J. V. Lee, “The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster,” BMB Reports, vol. 49, no. 2, pp. 81–92, 2016. View at Publisher · View at Google Scholar · View at Scopus
  25. C. T. Murphy and P. J. Hu, “Insulin/insulin-like growth factor signaling in C. elegans,” WormBook, pp. 1–43, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. M. J. Muñoz, “Longevity and heat stress regulation in Caenorhabditis elegans,” Mechanisms of Ageing and Development, vol. 124, no. 1, pp. 43–48, 2003. View at Publisher · View at Google Scholar · View at Scopus
  27. J. M. A. Tullet, M. Hertweck, J. H. An et al., “Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans,” Cell, vol. 132, no. 6, pp. 1025–1038, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. C. Kenyon, “A pathway that links reproductive status to lifespan in Caenorhabditis elegans,” Annals of the New York Academy of Sciences, pp. 1204–156, 2010. View at Google Scholar
  29. B. Gerisch, V. Rottiers, D. Li et al., “A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling,” Proceedings of the National Acadamy of Sciences of the United States of America, vol. 104, no. 12, pp. 5014–5019, 2007. View at Publisher · View at Google Scholar · View at Scopus