The Efficacy and Safety of a Herbal Toothpaste in Reducing Gingivitis: A Double-Blind, Randomized, Placebo-Controlled, Parallel Allocation Clinical Trial
Table 3
Percentage reductions in clinical indices at every follow-up.
Index
Time point
Group
Mean
P25
P50
P75
Std.
Mean difference
P value
PI
8 weeks -4 weeks
Control
-3.88
-11.27
-7.00
4.69
13.47
3.24
0.105
Test
-0.67
-8.41
-3.96
6.64
12.90
12 weeks -8 weeks
Control
2.44
-7.04
2.97
12.18
13.64
-1.53
0.286
Test
0.91
-9.40
-2.08
11.96
14.33
12 weeks -4 weeks
Control
-2.22
-10.90
-4.25
7.74
14.96
1.28
0.307
Test
-0.94
-6.97
-1.73
4.56
11.18
GI
8 weeks -4 weeks
Control
-4.41
-8.06
-4.14
1.61
7.30
-3.37
0.011
Test
-7.78
-14.22
-6.91
-1.27
7.68
12 weeks -8 weeks
Control
5.26
1.73
3.91
8.16
5.73
-8.55
<0.001
Test
-3.28
-7.87
-3.99
0.60
6.03
12 weeks -4 weeks
Control
0.42
-4.62
0.28
3.91
7.16
-11.46
<0.001
Test
-11.04
-15.46
-10.95
-5.83
6.70
BI
8 weeks -4 weeks
Control
-6.44
-11.85
-4.93
-1.54
9.30
-4.04
0.019
Test
-10.50
-20.87
-9.65
-1.60
10.57
12 weeks -8 weeks
Control
7.44
2.23
5.47
11.71
8.34
-11.49
<0.001
Test
-4.05
-8.42
-5.17
0.00
6.67
12 weeks -4 weeks
Control
0.18
-6.63
0.84
6.88
9.63
-14.57
<0.001
Test
-14.39
-22.27
-13.36
-7.11
9.52
BOP%
8 weeks 4 weeks
Control
-20.62
-65.68
-33.33
5.69
60.43
-7.78
0.257
Test
-28.40
-59.02
-43.65
-8.57
53.41
12 weeks -8 weeks
Control
158.66
21.37
68.11
167.80
231.47
-118.81
<0.001
Test
39.85
-31.26
8.11
57.50
124.37
12 weeks -4 weeks
Control
48.33
-18.97
15.14
67.17
96.18
-73.14
<0.001
Test
-24.81
-62.15
-40.27
-1.56
59.45
indicates statistical significance at p<0.05. aIndependent samples t test. bWilcoxon rank-sum test. cMean difference = test – control.
