Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Fig 3

Research Article

Da-Cheng-Qi Decoction Alleviates Intestinal Injury in Rats with Severe Acute Pancreatitis by Inhibiting the JAK2-STAT3 Signaling Pathway

Figure 3

The expression of STAT3 mRNA in the pancreas. (a) In the five groups, differences between 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significant (). (b) At four timepoints, differences between the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significant (). DCQD, Da-Cheng-Qi decoction; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; JAK2, Janus kinase 2; mRNA, messenger ribonucleic acid; p-JAK2, phosphorylated Janus kinase 2; p-STAT3, phosphorylated signal transducers and transcription 3; R, ruxolitinib-treated rats with severe acute pancreatitis; S, Stattic-treated rats with severe acute pancreatitis; SAP, severe acute pancreatitis; SO, sham operation; STAT3, signal transducers and transcription 3.

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