Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Tab 1

Research Article

Da-Cheng-Qi Decoction Alleviates Intestinal Injury in Rats with Severe Acute Pancreatitis by Inhibiting the JAK2-STAT3 Signaling Pathway

Table 1

Comparisons of the dynamic serum amylase levels.

Group3 hours6 hours12 hours18 hours

SO1589.5 ± 179.32910.5 ± 725.41600.5 ± 252.71637.1 ± 277.7
SAP6329.7 ± 1496.39951.0 ± 1825.7▲♂8523.9 ± 1359.9▲☆6784.0 ± 795.6▲◎
R3871.0 ± 1112.54689.4 ± 1059.3■♂5390.6 ± 1009.1■☆4754.9 ± 1197.8■◎
S4114.5 ± 979.45579.6 ± 956.9•♂6129.7 ± 1227.4•☆5157.2 ± 1127.8•◎
DCQD3219.5 ± 895.74272.8 ± 930.1◢♂4917.5 ± 990.6◢☆4037.8 ± 833.9◢◎

Note: The data are presented as U/L. In the SO group, 3 hours versus 6 hours and 6 hours versus 12 hours are significantly different (). In the SAP group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different (). In the R group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different (). In the S group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different (). In the DCQD group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different (). At 3 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. At 6 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. At 12 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. At 18 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. DCQD, Da-Cheng-Qi decoction; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; IL-4, interleukin 4; IL-6, interleukin 6; IL-10 interleukin 10; JAK2, Janus kinase 2; p-JAK2, phosphorylated Janus kinase 2; p-STAT3, phosphorylated signal transducers and transcription 3; R, ruxolitinib-treated rats with severe acute pancreatitis; S, Stattic-treated rats with severe acute pancreatitis; SAP, severe acute pancreatitis; SO, sham operation; STAT3, signal transducers and transcription 3; TNF-α, tumor necrosis factor alpha.

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