Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Tab 3

Research Article

Da-Cheng-Qi Decoction Alleviates Intestinal Injury in Rats with Severe Acute Pancreatitis by Inhibiting the JAK2-STAT3 Signaling Pathway

Table 3

Comparisons of the dynamic IL-6 levels.

Group3 hours6 hours12 hours18 hours

SO25.45 ± 6.1332.05 ± 7.6429.09 ± 7.8728.91 ± 8.79
SAP89.87 ± 16.37151.08 ± 15.37▲♂213.29 ± 19.59▲☆184.70 ± 15.86▲◎
R57.06 ± 22.85128.34 ± 19.93■♂180.66 ± 29.31■☆164.79 ± 29.48■◎
S64.53 ± 19.74139.86 ± 21.69•♂199.57 ± 27.04•☆177.02 ± 27.83•◎
DCQD50.59 ± 22.57120.82 ± 20.15◢♂168.15 ± 24.86◢☆141.30 ± 23.80◢◎

Note: The data are presented as pg/mL. In the SO group, 3 hours versus 6 hours and 6 hours versus 12 hours are significantly different (). In the SAP group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different (). In the R group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different (). In the S group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different ().In the DCQD group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different (). At 3 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. At 6 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. At 12 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. At 18 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. DCQD, Da-Cheng-Qi decoction; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; IL-4, interleukin 4; IL-6, interleukin 6; IL-10 interleukin 10; JAK2, Janus kinase 2; p-JAK2, phosphorylated Janus kinase 2; p-STAT3, phosphorylated signal transducers and transcription 3; R, ruxolitinib-treated rats with severe acute pancreatitis; S, Stattic-treated rats with severe acute pancreatitis; SAP, severe acute pancreatitis; SO, sham operation; STAT3, signal transducers and transcription 3; TNF-α, tumor necrosis factor alpha.

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