Da-Cheng-Qi Decoction Alleviates Intestinal Injury in Rats with Severe Acute Pancreatitis by Inhibiting the JAK2-STAT3 Signaling Pathway

Table 7

Comparisons of the protein expression of p-JAK2 in the terminal ileum.

Group	3 hours	6 hours	12 hours	18 hours
SO	0.446 ± 0.077	0.501 ± 0.085^★	0.574 ± 0.085^★	0.481 ± 0.095^★
SAP	0.802 ± 0.178^♀a	0.991 ± 0.182^▲♂a	1.345 ± 0.246^▲☆a	0.921 ± 0.181^▲◎a
R	0.661 ± 0.121^♀	0.910 ± 0.133^■♂	1.174 ± 0.221^■☆	0.885 ± 0.204^■◎
S	0.775 ± 0.168^♀a	0.950 ± 0.142^•♂a	1.321 ± 0.233^•☆a	0.922 ± 0.185^•◎a
DCQD	0.671 ± 0.127^♀	0.935 ± 0.142^◢♂	1.211 ± 0.212^◢☆	0.851 ± 0.196^◢◎

Note: The data are presented as the p-JAK2/GAPDH ratio. ^★In the SO group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different ().^▲In the SAP group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different (). ^■In the R group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different ().^•In the S group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different ().^◢In the DCQD group, 3 hours versus 6 hours, 6 hours versus 12 hours, and 12 hours versus 18 hours are significantly different (). ^♀At 3 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. ^♂At 6 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. ^☆At 12 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. ^◎At 18 hours, the SO group versus the SAP group, the SAP group versus the R group, the R group versus the S group, and the S group versus the DCQD group are significantly different. ^aAt the same timepoints, the SAP group versus the S group are not significantly different (). DCQD, Da-Cheng-Qi decoction; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; IL-4, interleukin 4; IL-6, interleukin 6; IL-10 interleukin 10; JAK2, Janus kinase 2; p-JAK2, phosphorylated Janus kinase 2; p-STAT3, phosphorylated signal transducers and transcription 3; R, ruxolitinib-treated rats with severe acute pancreatitis; S, Stattic-treated rats with severe acute pancreatitis; SAP, severe acute pancreatitis; SO, sham operation; STAT3, signal transducers and transcription 3; TNF-α, tumor necrosis factor alpha.