|
| Protein name | Gene name | Unipro ID | PPI network degree |
|
| RAC-alpha serine/threonine-protein kinase | AKT1 | P31749 | 27 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | PIK3CG | P48736 | 24 |
| Insulin receptor substrate 1 | IRS1 | P35568 | 22 |
| Leptin | LEP | P41159 | 22 |
| Mitogen-activated protein kinase 1 | MAPK1 | P28482 | 22 |
| Peroxisome proliferator activated receptor gamma | PPARG | P37231 | 21 |
| Tumor necrosis factor | TNF | P01375 | 20 |
| Glucagon | GCG | P01275 | 17 |
| Prostaglandin G/H synthase 2 | PTGS2 | P35354 | 17 |
| Nitric-oxide synthase, endothelial | NOS3 | P29474 | 16 |
| Phosphatidylinositol 3-kinase regulatory subunit alpha | PIK3R1 | P27986 | 16 |
| Apoptosis regulator Bcl-2 | BCL2 | P10415 | 15 |
| Estrogen receptor | ESR1 | P03372 | 15 |
| Insulin receptor | INSR | P06213 | 15 |
| Mitogen-activated protein kinase 14 | MAPK14 | Q16539 | 15 |
| Mitogen-activated protein kinase 3 | MAPK3 | P27361 | 15 |
| Interleukin-4 | IL4 | P05112 | 14 |
| Peroxisome proliferator-activated receptor alpha | PPARA | Q07869 | 13 |
| Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | PPARGC1A | Q9UBK2 | 13 |
| Heme oxygenase 1 | HMOX1 | P09601 | 11 |
| Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 | P14672 | 11 |
| C-C motif chemokine 2 | CCL2 | P13500 | 10 |
| Prothrombin | F2 | P00734 | 10 |
| Matrix metalloproteinase-9 | MMP9 | P14780 | 10 |
| Protein kinase C delta type | PRKCD | Q05655 | 10 |
| NAD-dependent protein deacetylase sirtuin-1 | SIRT1 | Q96EB6 | 10 |
| Sterol regulatory element-binding protein 1 | SREBF1 | P36956 | 10 |
| Androgen receptor | AR | P10275 | 9 |
| Leptin receptor, LEP-R | LEPR | P48357 | 9 |
| 1-Phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | PLCG1 | P19174 | 9 |
| Protein kinase C alpha type | PRKCA | P17252 | 9 |
| Protein kinase C beta type | PRKCB | P05771 | 9 |
| Tyrosine-protein phosphatase nonreceptor type 1 | PTPN1 | P18031 | 9 |
| Retinoic acid receptor RXR-alpha | RXRA | P19793 | 9 |
| Acetyl-CoA carboxylase 1 | ACACA | Q13085 | 8 |
| Tumor necrosis factor ligand superfamily member 6 | FASLG | P48023 | 8 |
| Protein kinase C epsilon type | PRKCE | Q02156 | 8 |
| Glycogen synthase kinase-3 beta | GSK3B | P49841 | 7 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | IKBKB | O14920 | 7 |
| Nitric oxide synthase, inducible | NOS2 | P35228 | 7 |
| 5′-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 | Q13131 | 7 |
| Glucose-6-phosphatase | G6PC | P35575 | 6 |
| 5-Hydroxytryptamine receptor 2C (by homology) | HTR2C | P28335 | 6 |
| 5′-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 | P54646 | 6 |
| Mitochondrial brown fat uncoupling protein 1 | UCP1 | P25874 | 6 |
| Beta-2 adrenergic receptor | ADRB2 | P07550 | 5 |
| Glucokinase | GCK | P35557 | 5 |
| 5-Hydroxytryptamine receptor 2A (by homology) | HTR2A | P28223 | 5 |
| 5-Hydroxytryptamine receptor 2B | HTR2B | P41595 | 5 |
| Phosphoenolpyruvate carboxykinase, cytosolic (GTP) | PCK1 | P35558 | 5 |
| Peroxisome proliferator-activated receptor delta | PPARD | Q03181 | 5 |
| Adenosine receptor A1 | ADORA1 | P30542 | 4 |
| Alpha-2A adrenergic receptor (by homology) | ADRA2A | P08913 | 4 |
| Alpha-2B adrenergic receptor | ADRA2B | P18089 | 4 |
| Alpha-2C adrenergic receptor | ADRA2C | P18825 | 4 |
| D(2) dopamine receptor (by homology) | DRD2 | P14416 | 4 |
| Hepatocyte nuclear factor 1-alpha | HNF1A | P20823 | 4 |
| Mitogen-activated protein kinase 10 | MAPK10 | P53779 | 4 |
| Glucocorticoid receptor | NR3C1 | P04150 | 4 |
| Acyl-CoA desaturase | SCD | O00767 | 4 |
| Solute carrier family 2, facilitated glucose transporter member 1 | SLC2A1 | P11166 | 4 |
| Mitochondrial uncoupling protein 2 | UCP2 | P55851 | 4 |
| Carnitine O-palmitoyltransferase 1, liver isoform | CPT1A | P50416 | 3 |
| D(1A) dopamine receptor | DRD1 | P21728 | 3 |
| 3-Hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | P04035 | 3 |
| Prostacyclin receptor | PTGIR | P43119 | 3 |
| Superoxide dismutase (Cu-Zn) | SOD1 | P00441 | 3 |
| Aldose reductase | AKR1B1 | P15121 | 2 |
| Cyclin-dependent-like kinase 5 | CDK5 | Q00535 | 2 |
| Aromatase | CYP19A1 | P11511 | 2 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | HSD11B1 | P28845 | 2 |
| Transcription factor AP-2-alpha | TFAP2A | P05549 | 2 |
| Vitamin D3 receptor | VDR | P11473 | 2 |
| Angiotensin-converting enzyme | ACE | P12821 | 1 |
| Dipeptidyl peptidase 4 | DPP4 | P27487 | 1 |
| Prostaglandin G/H synthase 1 | PTGS1 | P23219 | 1 |
|
