Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Fig 1

Research Article

Effects of Huazhuo Jiedu Shugan Decoction on Cognitive and Emotional Disorders in a Rat Model of Epilepsy: Possible Involvement of AC-cAMP-CREB Signaling and NPY Expression

Figure 1

Timeline of the experiment. Habitual feeding was conducted 7 days before the formal experiment. Epilepsy was induced by intraperitoneal injection of PTZ for 28 days. The model was maintained once per week for the next 28 days. The drug administration began on day 28 and continued for 28 days. The RAM test was performed from day 35 until day 63, the MWM test was performed from day 56 until day 63, the OFM and EPM tests were conducted from day 63 until day 70, the YM test was performed from day 70 until day 77, and immunohistochemistry was performed from day 56 until day 70.

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