Jwa Kum Whan Attenuates Nonalcoholic Fatty Liver Disease by Modulating Glucose Metabolism and the Insulin Signaling Pathway

Figure 4

Effects of JKW on OGTT, fasting glucose, serum insulin, and HOMA-IR indices in mice fed on the HFD. (a) Impact of JKW on blood glucose levels as determined by OGTT at the indicated times after glucose loading. (b) Fasting glucose and (c) serum insulin levels were determined in mice fed on HFD as described in Materials and Methods. (d) HOMA-IR indices were used to determine insulin resistance in JKW-treated mice and these were compared with those of HFD controls. Results represent means ± SDs (n=6). < 0.05 and < 0.01 versus the normal diet group. < 0.05 and < 0.01 versus the HFD-fed group.

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