Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Fig 1

Research Article

Oxidative Stress and TGF-β1/Smads Signaling Are Involved in Rosa roxburghii Fruit Extract Alleviating Renal Fibrosis

Figure 1

Cili alleviates the functional changes in kidneys after unilateral ureteral obstruction (UUO). Sixty rats were randomized to five groups: sham operation, UUO, UUO with losartan (UUO+losartan), UUO with moderate Cili dose (3 g/kg/d) (UUO+CL moderate), and UUO with high Cili dose (6 g/kg/d) (UUO+CL high). Biochemical markers indicative of kidney functions were measured, including (a) blood urea nitrogen (BUN), (b) serum creatinine (Scr), and (c) urine protein (Upro) levels. N=12/group. The results are expressed as mean ± standard deviation (SD). P<0.01 vs. the sham group; △△P<0.01 vs. the UUO group; ◆P<0.05 vs. the losartan group.

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