Danzhi Jiangtang Capsule Mediates NIT-1 Insulinoma Cell Proliferation and Apoptosis by GLP-1/Akt Signaling Pathway

Figure 4

The protein levels of GLP-1/Akt signaling pathway molecules. NIT-1 cells were cultured with rats’ serums containing high dose or low dose of DJC for 24h; then, they were additionally treated with 110⁻⁵ mmol⋅L⁻¹ GLP-1 receptor inhibition or 5umol⋅L⁻¹ AKT inhibition for another 24h. (a) The protein levels of PI3K/p-PI3K, Akt/p-Akt, FoxO1/p-FoxO1 in each group; (b) the grey value statistics of p-PI3K, p-Akt, and p-FoxO1. Data were shown as Mean ± SD. <0.05, <0.01, <0.001. (1) S.K. JIANG Zaifang, Shen Ying. “Zhu Futang Practice of Pediatrics, 8th ed,” People’s Medical Publishing House.

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