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Study type | Results | Study characteristics |
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Cross-sectional study comparing children from anthroposophic families and children with a non-anthroposophic lifestyle [28] | Past use of antibiotics: (i) anthroposophic children: 52% (ii) non-anthroposophic children: 90% (odds ratio (OR): 0.62, 95% CI: 0.43 - 0.91) | N = 295 anthroposophic children and 380 non-anthroposophic children, age 5-13 years. Sweden
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Cross-sectional study comparing children from anthroposophic families and children with a non-anthroposophic lifestyle [29] | Antibiotics use ever, in the first 12 months of life and after 12 months of life: (i) all significantly lower in children with an anthroposophic lifestyle (p < 0.001) | N = 6.630 children, age 5-13 years (4.606 from Steiner schools and 2.024 from reference schools) in 5 European countries (Austria, 11%; Germany, 39%; The Netherlands, 22%; Sweden, 9%; Switzerland, 20%)
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KOALA Birth Cohort Study comparing families with an alternative and a non-alternative lifestyle [30] | Families with an alternative lifestyle: (i) antibiotic use was less frequent (13.8% vs. 24.1%) (p-value not presented) | N= 2.343 conventional children and 491 alternative lifestyle children. The Netherlands |
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Observational study on prescribing practices of anthroposophic medicine (AM) doctors in the treatment of upper respiratory tract infections [31] | Prescription rate for antibiotics (6.3%) was well below the German average | 21.818 prescriptions for 12.081 patients (73.7% children) with 19.050 cases of URTI were analysed. Antibiotics were given in 6.3% of cases (minimum: common cold 1.9%, maximum: tonsillitis 24.3%). Germany |
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Prospective, non-randomised comparison of outcomes in patients self-selected to anthroposophic or conventional therapy under real-world conditions [10] | 5.5% of the patients in the AM group and 33.6% in the conventional group received antibiotics (p < 0.0001) | 29 primary care practices (Austria, Germany, Netherlands, UK and USA). N= 1.016 outpatients, age ≥ 1 month, consulting an anthroposophic (N = 715) or conventional physician (N = 301) with a chief complaint of acute (≤ 7 days) sore throat, ear pain, sinus pain, runny nose or cough |
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Prospective, non-randomised comparison of outcomes in patients self-selected to anthroposophic or conventional therapy under real-world conditions [32] | 5.5% of the patients in the AM group and 25.6% in the conventional group received antibiotics (p < 0.001) | N = 529 children <18 years from Europe (Austria, Germany, Netherlands, and UK) or USA with acute respiratory or ear infections |
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Observational study on the treatment of patients with upper respiratory tract infections: homeopathic GPs vs. conventional GPs [33] | Significantly lower consumption of antibiotics (OR = 0.43, 95% CI: 0.27-0.68) in the homeopathic patients group | N = 518 adults and children with URTI (79.3% rhinopharyngitis). France |
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Randomized trial, children 6 months to 11 years old, diagnosed with AOM and managed with a delayed antibiotic approach, randomized to standard therapy alone or standard therapy plus a homeopathic ear drop preparation [34] | Significantly less antibiotic use in the homeopathic group (26.9% vs. 41.2%) (p-value not presented) | N = 456 patient visits were compared: 281 received homeopathy, 175 received conventional medicine. Germany, Switzerland, Austria, USA |
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Observational study among parents of children [35] | Use of homeopathic products not associated with decreased antibiotic consumption (adjusted OR = 1.02, 95% CI: 0.84 - 1.24). | N = 9.723 parents of children, age: 3–4.5 years. United Kingdom |
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