Review Article

Acupuncture for Chronic Pain-Related Insomnia: A Systematic Review and Meta-Analysis

Table 1

Characteristics of included studies.

Study Study locationSample size
(male/female)
InterventionsTreatment periodOutcomesAdverse events

Su (2005)Guangdong, ChinaAG: 26/64
CG: 20/56
AG: MA
CG: drugs (Estazolam)
AG: once a day for 12 days, 30 min
CG: twice a day for 12 days
CENR
Huang (2010)USAAG: 6
CG: 6
AG: MA
CG: sham acupuncture
Two times per week for 4 weeks, followed by one time per week for 4 weeks, 30 minPSQI
Not serious, mild
Qiu (2014)Beijing, ChinaAG: 71/65
CG: 74/62
AG: MA
CG: drugs (Eszopiclone)
AG: once a day for 30 days, 30 min
CG: once a day for 30 days
CE
PSQI
VAS
Not serious, mild
Wang (2015)Sichuan, ChinaAG: 30
CG: 30
AG: MA
CG: drugs (Estazolam)
AG: once a day for 20 days, 30 min
CG: once a day for 20 days
PSQI
NR
Kui (2016)Guangdong, ChinaAG:16 /14
CG:15 /15
AG: MA
CG: sham acupuncture
Once a day for 2 weeks, 30 minCE
Not serious, mild
Zheng (2016)Guangdong, ChinaAG: 44/36
CG: 43/37
AG: MA
CG: drugs (Zaoren Anshen capsule)
AG: once a day for 20 days, 30 min
CG: once a day for 20 days
CE
PSQI
NR
Gu (2017)Zhejiang, ChinaAG: 24/16
CG: 22/18
AG: MA
CG: drugs (Alprazolam)
AG: once a day for 4 weeks, 30 min
CG: once a day for 4 weeks
CE
PSQI
VAS
Not serious, mild
Song (2017)Neimenggu, ChinaAG: 18/16
CG: 19/15
AG: MA
CG: drugs (Estazolam)
AG: once a day for 30 days, 30 min
CG: once a day for 30 days
CE
PSQI
VAS
NR
Yao (2018)Yunnan, ChinaAG: 10/23
CG: 10/23
AG: MA
CG: drugs (Eszopiclone)
AG: once a day for 20 days, 30 min
CG: once a day for 20 days
CE
PSQI
NR

AG, acupuncture group; CG, control group; CE, clinical effect; MA, manual acupuncture; NR, not reported; PSQI, the Pittsburgh Sleep Quality Index score; VAS, the visual analogue scale.