Estrogenic Effect of the Extract of QingYan Formula on Reproductive Tissues in Immature Mice

Figure 1

The effect of QingYan formula extract (QYFE) on the estrous cycle in immature mice (200×). Smears from control group consisted of leukocytes, confirming a state of diestrus. Smears from immature mice treated with estradiol valerate (EV) or QYFE showed a large number of keratinized epithelial cells, indicating that both EV and QYFE can promote keratinization of the superficial vaginal epithelium and advanced estrus. (I) The control group untreated; (II) treated with EV; (III) treated with QYFE (4 g/kg).