Jie Du Tong Ye San Prevents N-Nitrosomethylbenzylamine-Induced Esophageal Carcinogenesis via Inhibition of Inflammation and Proliferation
Effects of JDTYS on expression of proliferation markers in the rat at week 35. (a) Immunohistochemistry analysis was used to determine the level of Ki67 in the ZSP, JDTYS 10 g/kg, and JDTYS 25 g/kg groups compared with the NMBA group; there were significant differences (200×; P<0.05, P<0.01, P<0.001). (b) Immunohistochemistry analysis for c-Jun: the expression levels of c-Jun were significantly inhibited in the ZSP, JDTYS 10 g/kg, and JDTYS 25 g/kg groups compared with the NMBA group (200×; P<0.05, P<0.01, P<0.001).
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