Nerol Attenuates Ouabain-Induced Arrhythmias

Figure 3

Protective effects of nerol on ouabain-induced arrhythmias in guinea pig hearts. (a) Representative recording of effects of ouabain (Ouab, 50 μM) on left ventricular developed pressure (LVDP, Top panel), nerol (30 and 300 μM) + ouabain (middle), and nifedipine (0.35 μM) + ouabain (botton). Summary of effects of nerol or nifedipine preincubation on the onset time of arrhythmia (b), inotropic response (c), tonotropic effect (d), and inotropic response rate (dP/dt) induced by ouabain (e), respectively. Data are represented as means ± SEM (n = 5 - 6, p<0.05 versus Ouab). One-way ANOVA followed was by Tukey’s post hoc test.

(a)

(b)

(c)

(d)

(e)