Detarium microcarpum, Guiera senegalensis, and Cassia siamea Induce Apoptosis and Cell Cycle Arrest and Inhibit Metastasis on MCF7 Breast Cancer Cells

Table 1

Cell viability assay. The viability of MCF7 cells was determined using PrestoBlue dye following 72-hour treatment with the plant extracts. Detarium microcarpum methanol extract (DMME), Cassia siamea methanol extract (CSME), Guiera senegalensis methanol extract (GSME), Detarium microcarpum aqueous extract (DMAE), Cassia siamea aqueous extract (CSAE), and Guiera senegalensis aqueous extract (GSAE).

Concentration (µg/ml)	Percentage cell viability
	DMME	DMAE	GSME	GSAE	CSME	CSAE
15.625	92.87 ± 8.10	121.96 ± 6.01	101.78 ± 2.41	119.75 ±1.99	80.27 ± 6.39	113.12 ± 2.17
31.25	90.41 ± 14.32	105.11 ± 0.00	107.25 ± 6.02	88.54 ± 8.54	82.83 ± 7.79	117.40 ± 1.27
62.5	80.04 ± 13.51	59.94 ± 0.00	68.78 ± 3.23	91.02 ± 7.32	100.11 ± 4.02	122.10 ± 1.13
125	51.51 ± 2.68	33.98 ± 0.00	64.10 ± 0.00	54.97 ± 3.09	51.28 ± 4.02	116.44 ± 0.73
250	29.10 ± 0.10	22.51± 4.71	38.13 ± 5.04	32.18 ± 0.00	36.34 ± 4.57	119.34 ± 1.70
500	34.26 ± 3.97	33.01 ± 3.55	25.75 ± 1.26	36.33 ± 0.00	13.77 ± 5.18	93.51 ± 14.17