Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Tab 6

Research Article

GC-MS Analysis and Inhibitory Evaluation of Terminalia catappa Leaf Extracts on Major Enzymes Linked to Diabetes

Table 6

Drug-likeness violation of selected virtual screened hit compounds.

S. noCompoundMWLog PHAHD# Lipinski violations

1Ethyl-α-D-glucopyranoside208.21−2.1864
2n-Hexadecanoic acid256.424.1921
3Phytol296.535.25111
4Vitamin E430.716.14211
5Acarbose645.6−6.9419143
6Lipinski rule details≤500≤5≤10≤5

MW: molecular weight; log P: octanol-water partition coefficient; HA: hydrogen acceptor; HD: hydrogen donor.

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