Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Tab 3

Review Article

An Overview of the Randomized Placebo-Controlled Trials of Chinese Herbal Medicine Formula Granules

Table 3

Comparison of the cure rate between CHM formula granules and placebo based on conventional therapy.

Study IDTreatmentPlaceboP value
n/N%n/N%

Chronic Hepatitis B: HBV DNA negative after 48-week treatment
Zhan BL 201324/3080.0016/3053.330.07

Chronic Hepatitis B: HBeAg negative after 48-week treatment
Ye YA 201283/28029.6450/28017.860.001
Zhan BL 201314/3046.676/3020.000.04
Meta-analysis RR and 95% CI: 1.73 ; I2 = 0%

Chronic Hepatitis B with YMDD: HBV DNA negative after 48-week treatment
Xie WN 20167/3619.441/333.030.07

Chronic Hepatitis B with YMDD: HBeAg negative after 48-week treatment
Xie WN 20169/3625.000/310.000.05

Herpes simplex keratitis: Symptoms disappeared and normal laboratory test
Song JK 201624/3372.7314/3145.160.03
Song JK 2016a23/3467.6513/3240.630.04

Depression: The score of HAMD-17 <7
Liu J 201212/3237.508/3324.240.25

Myasthenia gravis: Reduction of the score of myasthenia gravis scale≥95
Shuang XP 20140/200.000/180.00-

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