Review Article
An Overview of the Randomized Placebo-Controlled Trials of Chinese Herbal Medicine Formula Granules
Table 5
Comparison of the effectiveness rate between CHM formula granules and placebo based on conventional therapy.
| | Study ID | Treatment | Placebo | P value | | n/N | % | n/N | % |
| | COPD: the comprehensive improvement of pulmonary function, dyspnoea classification, 6-min walking distance and BMI | | Chen SQ 2017(stable period) | 56/60 | 93.33 | 48/60 | 80.00 | 0.04 | | Xie WY 2017(acute period) | 57/60 | 95.00 | 53/60 | 88.33 | 0.19 | | Shang LZ 2017 | 92/100 | 92.00 | 80/100 | 80.00 | 0.02 | | Meta-analysis RR and 95% CI: 1.13 ; I2 = 0% |
| | Diabetic peripheral neuropathy: Pain relief and neurological function improvement | | Hu WH 2015 | 42/48 | 87.50 | 33/47 | 70.21 | 0.04 |
| | Depression: Reduction in HAMD Scale ≥25 | | Liu J 2012 | 28/32 | 87.50 | 25/33 | 75.76 | 0.23 |
| | Angina pectoris: Pain relieved, attacks reduced, ECG improved, nitro-glycerine reduced by 50-80 | | Pang LJ 2013 | 22/29 | 75.86 | 16/24 | 66.67 | 0.47 |
| | Myasthenia gravis: Reduction of the score of myasthenia gravis scale≥25 | | Shuang XP 2014 | 18/20 | 90.00 | 16/18 | 88.89 | 0.91 |
| | Herpes simplex keratitis: Symptoms improved and almost normal laboratory test | | Song JK 2016 | 33/33 | 100.00 | 31/31 | 100.00 | 1.00 | | Song JK 2016a | 34/34 | 100.00 | 30/32 | 93.75 | 0.23 |
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