Research Article
Network Pharmacology-Based Prediction and Verification of the Targets and Mechanism for Panax Notoginseng Saponins against Coronary Heart Disease
Table 3
Top 10 KEGG pathways of common genes in PNS against CHD.
| Geneset | Description | Count | P-Value | FDR | Ratio |
| hsa04926 | Relaxin signaling pathway | 6 | 0.000001 | 0.000182 | 18.143 | hsa05219 | Bladder cancer | 4 | 0.000003 | 0.000465 | 38.352 | hsa04915 | Estrogen signaling pathway | 4 | 0.000300 | 0.027039 | 11.477 | hsa05418 | Fluid shear stress and atherosclerosis | 4 | 0.000400 | 0.027039 | 11.312 | hsa05205 | Proteoglycans in cancer | 4 | 0.001400 | 0.061165 | 7.823 | hsa04370 | VEGF signaling pathway | 3 | 0.000400 | 0.027039 | 19.988 | hsa04211 | Longevity regulating pathway | 3 | 0.001400 | 0.061165 | 13.251 | hsa04657 | IL-17 signaling pathway | 3 | 0.001600 | 0.061165 | 12.681 | hsa01522 | Endocrine resistance | 3 | 0.001800 | 0.061165 | 12.034 | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 3 | 0.001900 | 0.061165 | 11.912 |
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