Hypoglycemic and Toxic Effect of Morus mesozygia Leaf Extract on the Liver and Kidneys of Alloxan-Induced Hyperglycemic Wistar Rats

Figure 4

Microphotograph of the kidney (H&E, ×200) of alloxan-induced hyperglycemic adult wistar rats exposed to 200 mg, 400 mg, and 800 mg of Morus mesozygia for 14 days. Kidneys of diabetic control rats showed focal necrosis at the corticomedullary junction (black arrow heads). There was mild congestion in the 200 mg group. No significant lesions were observed in the 400 mg and 800 mg groups. Note: C-areas of focal necrosis; H&E = hematoxylin and eosin. (a) Diabetic control group. (b) 200 mg group. (c) 400 mg group. (d) 800 mg group. (e) Glibenclamide group.

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