Effect of Xueniao Capsule on Escherichia coli-Induced Acute Pyelonephritis Rats by ¹H NMR-Based Metabolomic Approach

Table 2

Comparison of the integral levels of metabolites in eight groups.

Metabolites	δ (ppm)	VIP	APN	Change trend						Recovery rates (%)
				APN + N	APN + XNC	APN + PE	APN + EA	APN + BU	APN + W	APN + N	APN + XNC	APN + PE	APN + EA	APN + BU	APN + W
Lactate	1.33	9.04	↑	↓	↓	↓	↓	↓	↓	67.81	61.72	18.01	18.11	28.89	37.57
Choline	3.21	6.52	↑	↓	↓	↓	↓	↓	↓	53.10	47.73	19.99	24.16	36.47	16.76
Glutamate	2.36	2.83	↑	↓	↓	↓	↓	↓	↓	26.01	40.02	27.39	45.94	9.32	17.08
Fumarate	6.53	1.01	↑	↓	↓	—	↓	—	↓	59.75	69.50	—	80.91	—	42.74
Succinate	2.41	1.92	↑	↓	↓	↓	↓	↓	↓	111.21	124.09	71.95	53.85	114.45	53.89
Glutamine	2.13	1.60	↑	↓	↓	↓	↓	↓	↓	59.53	28.35	41.81	46.61	52.20	46.14
Acetate	1.93	6.41	↑	↓	↓	—	—	—	—	62.80	84.94	—	—	—	—
Myo-inositol	3.53	1.53	↑	↓	↓	↓	↓	↓	↓	42.30	35.81	24.93	26.96	30.34	6.22
Ethanolamine	3.15	1.28	↑	—	↓	—	—	—	—	—	138.10	—	—	—	—
Valine	1.05	1.27	↓	↑	↑	↑	↑	↑	↑	113.45	117.47	83.79	73.56	90.46	81.38
TMA	2.88	1.05	↓	↑	↑	↑	↑	↑	↑	92.11	82.73	42.64	86.78	46.48	89.34
DMG	2.91	1.14	↓	↑	↑	—	↑	—	↑	36.92	42.31	—	23.08	—	55
Alanine	1.49	1.14	↓	↑	—	↑	—	—	↑	44.35	—	7.17	—	—	9.44
Serine	3.97	1.74	↓	↑	↑	—	—	—	—	55.13	26.97	—	—	—	—
Betaine	3.91	3.28	↓	↑	—	—	—	—	↑	27.52	—	—	—	—	29.99
Aspartate	2.81	2.33	↓	↑	—	—	—	—	—	144.68	—	—	—	—	—
Efficacy index (EI)										996.67	899.74	337.68	479.96	408.61	485.55

Compared with the NS group, , ; compared with the APN group, , .