Alpinia oxyphylla Fruit Extract Ameliorates Experimental Autoimmune Encephalomyelitis through the Regulation of Th1/Th17 Cells

Figure 6

Effects of AO-1 on inflammatory cytokine production in -peptide-stimulated splenocytes. (a) Cell viability. (b) IFN-γ, (c) IL-2, and (d) TNF-α expression. C57BL/6 mice were immunized with peptide and splenocytes were isolated after 21 days. Splenocytes were treated with peptide and AO-1 for 48 h. Cell viability was assayed using the MTT method, and cytokine production was determined through ELISA. Date are expressed as mean ± SEM. P < 0.05 and P < 0.001 compared with vehicle group.

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