Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Fig 5

Research Article

Alcohol Induces More Severe Fatty Liver Disease by Influencing Cholesterol Metabolism

Figure 5

Mice fed 4% alcohol and 0.5% cholesterol LD impacted cholesterol metabolism in liver for feeding 5 weeks. (a–i) Immunohistochemistry reflected the expression of LDLR, PPARα, SREBP2, SREBP1, CYP7A1, ABCG5, and ABCG8 in liver and NPC1L1 in small intestine (x 400). (j) Western blot reflected the expression of HMGCR in liver. Values were expressed as the mean ± SD (n=3). #P < 0.05; ## P < 0.01 versus NLG; P < 0.05; ∮∮P < 0.01 versus CLG.

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