Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Fig 6

Research Article

Safflower Yellow B Protects Brain against Cerebral Ischemia Reperfusion Injury through AMPK/NF-kB Pathway

Figure 6

Effects of SYB on the AMPK/ NF-κB pathway in PC12 cells. PC12 were pretreated with SYB and subjected to I/R for 24 h; then the proteins in nuclear and cytoplasm were lysed by nuclear and cytoplasmic extraction reagent kits (a). Effects of SYB on the expression levels of NF-κB p65 and P-IκB-α in cytoplasm of PC12 cells (b). Effects of SYB on the expression levels of NF-κB p65 in nuclear of PC12 cells (c). Effects of SYB on the phosphorylation levels of AMPK in PC12 cells (d). Effects of SYB on the phosphorylation levels of ACC in PC12 cells. Data were presented as mean ± SD. ##P<0.01 versus control group; .05; .01 versus I/R group.
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