Determination of Electroacupuncture Effects on circRNAs in Plasma Exosomes in Diabetic Mice: An RNA-Sequencing Approach

Table 6

The top 10 pathway enrichment of upregulated differentially expressed host linear transcripts affected by EA intervention.

Pathway	Selection counts		False discovery rate	Differentially expressed genes
Thyroid hormone signaling pathway	5	<0.05	<0.05	MED13, MED13L, NCOA2, PIK3CB, SLC16A10
Glycosphingolipid biosynthesis-ganglio series	2	<0.05	<0.05	ST3GAL5, ST6GALNAC3
cGMP-PKG signaling pathway	4	<0.05	<0.05	ADCY9, PDE5A, PIK3CB, ROCK1
Transcriptional misregulation in cancer	4	<0.05	<0.05	ETV6, MLLT3, TGFBR2, ZEB1
Choline metabolism in cancer	3	<0.05	<0.05	PCYT1A, PDGFD, PIK3CB
Rap1 signaling pathway	4	<0.05	<0.05	ADCY9, FYB, PDGFD, PIK3CB
Regulation of actin cytoskeleton	4	<0.05	<0.05	IQGAP2, PDGFD, PIK3CB, ROCK1
AMPK signaling pathway	3	<0.05	<0.05	ACACA, PIK3CB, RAB14
Platelet activation	3	<0.05	<0.05	ADCY9, PIK3CB, ROCK1
Regulation of lipolysis in adipocytes	2	<0.05	<0.05	ADCY9, PIK3CB