Research Article
The Effect of Compound Sophora on Fluorouracil and Oxaliplatin Resistance in Colorectal Cancer Cells
Figure 3
Effect of compound radix Sophorae injection on the mRNA levels of genes. 5-FU/SW480 and L-OHP/SW480 cells were incubated with a nontoxic dose of compound radix Sophorae Flavescentis injection for 48 h as described above. P-gp and ABCG2 mRNA expression levels were significantly decreased in the two drug-resistant strains (5-FU/SW480 and L-OHP/SW480). ANXA1 expression was significantly increased, as determined by RT-PCR ().
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