Research Article
Short-Term Safety and Tolerability of an Antimalarial Herbal Medicine, CoBaT-Y017 in Healthy Volunteers
Table 1
Effects of CoBaT-Y017 administration on evolution of haematological parameters.
| | Haematological parameters | Inclusion D0 | Product Administration Days | Observation Days | Pvalue
| | D1 | D2 | D3 | D4 | D5 | D7 |
| | Hb | 14.2 ± 0.6 | 14.2 ± 0.6 | 14.0 ± 0.7 | 14.1 ± 0.9 | 14.1 ± 0.8 | 14.1 ± 0.7 | 14.0 ± 0.8 | 0.46 | | NRx109 | 4.9 ± 1.8 | 5.1 ± 0.6 | 5.1 ± 0.5 | 5.2 ± 0.7 | 5.1 ± 0.6 | 5.0 ± 0.6 | 5.0 ± 0.7 | 0.50 | | NWx103 | 4.9 ± 0.9 | 4.9 ± 0.6 | 5.0 ± 1.3 | 4.9 ± 0.6 | 5.0 ± 0.7 | 4.9 ± 1.3 | 4.8 ± 0.7 | 0.87 | | Plat.x105 | 2.0 ± 0.4 | 2.4 ± 0.6 | 2.2 ± 0.6 | 2.1 ± 0.6 | 2.2 ± 0.6 | 2.2 ± 0.6 | 2.1 ± 0.5 | 0.18 | | TP | 74.8 ± 10.8 | 72.4 ± 10.7 | 73.4 ± 11.0 | 73.4 ± 9.5 | 70.0 ± 12.0 | 77.1 ± 12.0 | 73.7 ± 13.7 | 0.23 |
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Legend: D: day; Hb: haemoglobin; NR= number of Red cells; NW= number of white cells; Plat: platelet; TP: prothrombin rate.
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