Research Article

Based on HIF-1α/Wnt/β-Catenin Pathway to Explore the Effect of Qingshen Granules on Chronic Renal Failure Patients: A Randomized Controlled Trial

Table 4

Comparison of HIF-1α, Wnt1, β-catenin, α-SMA, and E-cadherin levels (M ± SD).

VariableTreatment groupControl grouptP

HIF-1α(ng/ml)pre1.71±0.331.76±0.31-0.6720.504
post0.66±0.161.39±0.1719.846≤0.001
Wnt1(pg/ml)pre378.2±88.0382.5±85.4-0.2240.823
post314.2±85.8382.8±85.3-3.584=0.001
β-catenin(pg/ml)pre462.6±13.6461.7±16.70.2660.719
post416.5±13.6462.1±15.1-14.176≤0.001
α-SMA(KU/L)pre25.9±4.626.2±5.0-0.2790.781
post20.5±3.123.5±4.1-3.754≤0.001
E-cadherin(ng/ml)pre2553.5±404.42520.2±505.70.0130.897
post2166.9±398.62370.7±468.0-2.0970.039