Research Article
Network Pharmacology Deciphering Mechanisms of Volatiles of Wendan Granule for the Treatment of Alzheimer’s Disease
Table 3
GO enrichment analyses using database DAVID.
| | Category | Term | Count | % | P-Value | Benjamini |
| | BP | response to drug | 9 | 0.2 | 3.20E-08 | 3.10E-06 | | G-protein coupled receptor signalling pathway | 9 | 0.2 | 1.00E-04 | 2.80E-03 | | adenylate cyclase-activating adrenergic receptor signalling pathway | 8 | 0.2 | 1.00E-15 | 3.80E-13 | | cell-cell signalling | 7 | 0.1 | 4.00E-06 | 2.50E-04 | | positive regulation of vasoconstriction | 6 | 0.1 | 2.10E-09 | 3.90E-07 | | signal transduction | 6 | 0.1 | 4.60E-02 | 3.10E-01 |
| | CC | plasma membrane | 23 | 0.5 | 1.70E-09 | 5.90E-08 | | integral component of plasma membrane | 20 | 0.4 | 6.90E-15 | 4.70E-13 | | integral component of membrane | 16 | 0.3 | 6.60E-03 | 3.40E-02 | | postsynaptic membrane | 8 | 0.2 | 3.20E-08 | 7.30E-07 | | cell junction | 8 | 0.2 | 5.90E-06 | 8.20E-05 |
| | MF | drug binding | 6 | 0.1 | 1.80E-07 | 1.10E-05 | | protein heterodimerization activity | 6 | 0.1 | 1.10E-03 | 1.40E-02 | | protein homodimerization activity | 6 | 0.1 | 7.50E-03 | 8.00E-02 | | epinephrine binding | 5 | 0.1 | 1.10E-10 | 1.30E-08 | | GABA-A receptor activity | 4 | 0.1 | 4.30E-06 | 1.80E-04 | | extracellular ligand-gated ion channel activity | 4 | 0.1 | 2.40E-05 | 4.90E-04 |
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