Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Fig 4

Research Article

Anemoside B4 Protects Rat Kidney from Adenine-Induced Injury by Attenuating Inflammation and Fibrosis and Enhancing Podocin and Nephrin Expression

Figure 4

Pathological changes of the rat kidney induced by adenine after the intravenous administration of B4. (a) Morphology of the kidney. The black arrows showed the adenine crystallizes. (b) MRM of B4. The retention time of B4 was at 4.43min. (c) Mass spectrum (MS/MS) of B4. The m/z was 136. (d) The standard curve of B4. (e)-(f) Content of adenine in the kidney (e) and urine (f). (g) Ratio of the adenine in kidney to the adenine in urine. The data were shown as mean ± SEM from 7-10 rats in each group. #, compared with the control, P < 0.05. , compared with model groups, P < 0.05.

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